Optical Tweezers/TIRF system is an integrated platform enables users to control, manipulate and observe samples in real time with nanometer precision and femtoNewton resolution. The NanoTracker™ 2 optical tweezers module enables trapping and tracking samples from several µm down to 30nm by using a highly focused 1064nm laser beam for sensitive manipulation, force, and tracking experiments. The iLAS2 ring-TIRF Unit with 4 laser lines (405nm, 488nm, 561nm, and 640nm) is also attached to this system for TIRF imaging.
Applications:
- Quantitative force measurements
- Molecular motor mechanics
- Binding/elasticity of DNA and proteins
- Cell membrane dynamics and particle uptake into cells
- TIRF Imaging
Detailed Configuration
Standard Operation Protocol – Optical Tweezers/TIRF System
Staff-in-charge: Ms ZHU, Hanqi | 3910-3995 |imaging.cpos@hku.hk
