Technology Overview
The Mission Bio Tapestri Platform can perform targeted DNA sequencing in thousands of cells. It can detect single-nucleotide variations (SNV), indels, copy number variations (CNV), etc., at the single-cell level.
Mission Bio provides a portfolio of pre-designed panels covering the most commonly implicated genes in hematologic malignancies and solid tumors. For more flexibility, one can also create a custom panel based on current designs or from scratch for human, mouse or other genomes.
The Tapestri instrument employs a two-step microfluidic workflow. It first encapsulates single cells and performs cell barcoding. Next, barcoded cells will undergo targeted multiplex PCR and further processed to generate Illumina compatible libraries for next-generation sequencing.
Our Core currently hosts the Tapestri instrument. Service will be available later this year. Please feel free to contact us for details of service.
Contact
Dr KWOK, Hin
Ms CHENG, Lilian
